Lecture 1. The Coagulation System | Live Site July 10 2025a

Gerald A Soff MD

Presentation Date:

September 4, 2025

About This Lecture

Understanding the Coagulation System is a core part of the foundation for understanding thrombosis and hemostasis. This presentation will review the history and current understanding of the "Coagulation Cascade.

Slide Deck

Continuing Education Credit

Gerald A Soff MD

Chief, Classical Hematology Service
University of Miami Health System/Sylvester Comprehensive Cancer Center
Email: gas199@miami.edu

Speaker Disclosures

Disclosures for Gerald A Soff MD
Research Support (Past 2 years):
Amgen, Sobi/Dova Pharmaceuticals
Anthos Therapeutics

Data Safety Monitoring Committee
Alpine Immune Sciences

Advisory Boards (Past 2 years)
Sanofi , Novartis

Learning Objectives

1. Review the Structure and function of the coagulation Factors.
2. Review the concept of the cell/surface model of assembly of the various coagulation complexes.
3. Review the current understanding of the coagulation "cascade."
4. Review the physiologic anticoagulant processes.