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Lecture 9: Immune Thrombocytopenia (ITP)
Cindy Neunert MD
Presentation Date:
October 31, 2024
> Immune Thrombocytopenia (ITP) is associated with thrombocytopenia, due to immune platelet destruction.
> It has been over 70 years since an immune mechanism of platelet destruction was recognized, but more detailed understanding of the pathophysiology continues evolve.
> Therapeutic options are also increasing and in this presentation we will review the different modalities.
Cindy Neunert MD
Professor, Pediatrics
Section Head, Pediatric Hematology
Columbia University Medical Center
cn2401@cumc.columbia.edu
Disclosures
> Advisory Board: Janssen, UK ITP Association, Australian ITP Association
> Honorarium: Novartis, Sanofi, Argenx, Sobi
> Royalties: Up to Date
> Research Funding: Novartis
> In 1950, William Harrington injected blood from a patient with ITP into himself.
> He developed thrombocytopenia, which was severe but transient.
> This, and other subsequent similar experiments, indicated that ITP was due to a transmissible factor, as the first evidence of an immune mediated component to ITP.
> Harrington et al. J Lab Clin Med 1951;38:1-10
Starting in 2025, lectures are eligible for Continuing Education Credit.
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