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Lecture 31:Treatment of Iron Deficiency

Michael Auerbach MD, FACP
Presentation Date: 
May 8, 2025
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Presenter: Michael Auerbach MD, FACP
Private Practice, Baltimore, Maryland
Clinical Professor of Medicine
Georgetown University School of Medicine, Washington, DC
mauerbachmd@abhemonc.com

Iron Deficiency remains a major, global health
> Almost three billion cases worldwide
> In top five causes of years lived with disability worldwide
> Leading cause of years lived with disability in LMIC countries
> Leading cause of years lived with disability across 35 countries
Pasricha et al, Lancet, 2021

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> Preipheral smear of patient with iron deficiency anemia.

> The red cells show classic increased ccentral pallor.  Normally the central pallor of a red cell represents appropximately 1/3 of the diameter.  In iron deficiency, decreased hemoglobin content in the red cell leads to increased central pallor and smaller cells than normal.

>  This is referred to as hypochromic/microcytic anemia, and is classic for IDA and thalassemia.

> Image from Gerald A Soff MD

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