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Lecture 29: Thrombotic Microangiopathies/TTP
Mari Thomas MD, PhD
Presentation Date:
April 24, 2025
Dr. Mari Thomas
University College London Hospitals, UK
> Thrombotic Microangiopathies are a range of disorders, characterized by microvascular thrombosis, non-immune hemolytic anemia, and thrombocytopenia.
> These may be life-threatening, and require prompt diagnosis and appropriate intervention.
Peripheral smear from a patient with sepsis. Note thrombocytopenia, but also schistocytes (Fragmented red cells). This is consistent with Disseminated intravascular coagulation (DIC). (Image from Gerald A Soff MD)
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