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Lecture 19: Sickle Cell Disease

Thomas Harrington MD
Presentation Date: 
February 13, 2025
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Thomas Harrington, MD
University of Miami/Sylvester Comprehensive Cancer Center
tharring@med.miami.edu

> Sickle Cell Disease (SCD) was first described in 1910.

> SCD was the first disease where a specific mutation
was linked with a hereditary disease. (Pauling, L., Itano, H.A., Singer, S.J. & Wells, I.C. Sickle cell anemia: a molecular disease. Science 110 , 543–548 (1949).)

> While it remains a burden to affected individuals, and their families, research has led to important breakthroughs in management.

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Image Provided to Public access by: Janice Haney Carr, Sickle Cell Foundation of Georgia Jackie George, Beverly Sinclair, USCDCP

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