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Lecture 14: Antiphospholipid Antibody Syndrome
Shruti Chaturvedi, MBBS, MS
Presentation Date:
January 9, 2025
> A pro-thrombotic syndrome:
Clinically syndrome, associated with arterial and/or venous thrombosis, and or pregnancy complications.
> Laboratory features: Lupus Anticoagulant, and/or antibodies to beta-2-glycoprotein-1 or cardiolipin.
> Despite decades of clinical research and experience, the pathophysiology remains subject to debate.

Shruti Chaturvedi, MBBS, MS
Johns Hopkins School of Medicine
Baltimore, MD, USA
schatur3@jhmi.edu
Membership on advisory board: Sanofi Genzyme, Alexion, Takeda, Sobi, Novartis
• Honoraria: Dynamed.com
• Royalties: UpToDate.com
• Research support (to institution): Takeda, Sanofi, Argenx, Sobi
• Board of directors: United States TMA Consortium, HTRS

Image: C. Lockard Conley, founder of the Division of Hematology at the Johns Hopkins School of Medicine, first described the "Lupus Anticoagulant," an in vitro factor that interfered with coagulation in vitro, but was not associated with bleeding.
Starting in 2025, lectures are eligible for Continuing Education Credit.
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