Lecture 9: Immune Thrombocytopenia (ITP)

Cindy Neunert MD

Presentation Date:

November 6, 2025

About This Lecture

Immune Thrombocytopenia (ITP) is associated with thrombocytopenia, due to immune platelet destruction.
It has been over 70 years since an immune mechanism of platelet destruction was recognized, but more detailed understanding of the pathophysiology continues evolve.
Therapeutic options are also increasing and in this presentation we will review the different modalities.

Slide Deck

Continuing Education Credit

Cindy Neunert MD

Professor, Pediatrics
Section Head, Pediatric Hematology
CUIMC Columbia University Irving Medical Center

Speaker Disclosures

Disclosures:
> Advisory Board: Janssen, UK ITP Association, Australian ITP Association
> Honorarium: Novartis, Sanofi, Argenx, Sobi
> Royalties: Up to Date
> Research Funding: Novartis

Learning Objectives

1. Review the pathophysiology of ITP
2. Discuss the diagnosis of ITP
3. Outline first- line management
4., Provide an overview of second- line treatment strategies
5. Highlight third-line agents and novel agents in development