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Lecture 4: Von Willebrand Disease

Peter A. Kouides MD

Presentation Date: 

September 25, 2025

About This Lecture

  • Von Willebrand “Disease” is actually a group of bleeding disorders.

  • There are a range of types of vWD. 

  • The nature of the protein defect determines the inheritance pattern and clinical manifestations.

Speaker Disclosures

Consultant to Uniqure FIX gene therapy trial
Consultant to Tremeau Inc on a hemophiliac arthropathy trial

Learning Objectives

1. Review the structure and function of von Willebrand Factor
2. Review the different types of von Willebrand Disease (vWD)
3. Review the clinical manifestations of vWD
4. Review the different treatment options for vWD, depending on the type.

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