Lecture 3: Laboratory Tests of Hemostasis, Part 2

Gerald A Soff MD

Presentation Date:

September 18, 2025

About This Lecture

Laboratory testing of coagulation provides the tools to diagnose patients with thrombosis and hemorrhage. In this presentation, we will review the state-of-the-art for testing for acquired and hereditary hypercoagulable states.

Slide Deck

Continuing Education Credit

Gerald A Soff MD

Chief, Classical Hematology Service
University of Miami Health System/Sylvester Comprehensive Cancer Center
Email: gas199@miami.edu

Speaker Disclosures

Disclosures for Gerald A Soff MD.
Research Support (Past 2 years):
Amgen, Sobi/Dova Pharmaceuticals
Anthos Therapeutics

Data Safety Monitoring Committee
Alpine Immune Sciences

Advisory Boards (Past 2 years)
Sanofi , Novartis

Learning Objectives

Part 2: Laboratory Tests of Thrombotic Disease.
> Describe the pathophysiology of heparin-induced thrombocytopenia and discuss the appropriate use of screening and confirmatory tests.
> Discuss the test principle and interpretation of confirmatory tests of the Lupus Anticoagulant assays
> List appropriate laboratory evaluation of patients with suspected inherited thrombophilia.
> Discuss the effect of therapeutic anticoagulants on the reliability of results of clot based, chromogenic, immunologic and molecular tests.