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Lecture 23: Pre-Transfusion Testing: Fundamentals of Blood Typing & Cross Match

Monika Paroder, MD PhD

Presentation Date: 

March 19, 2026

About This Lecture

  • Transfusion medicine and availability of safe blood products is an essential aspect of all modern medicine. 

  • This is the first of three presentations from the Transfusion Medicine group at Montefiore Medical Center/Albert Einstein College of Medicine.

Speaker Disclosures

Disclosures: None

Learning Objectives

1. Describe different blood groups/ blood group antigens and understand what determines their clinical relevance
2. Understand why pretransfusion testing is performed, the components of pretransfusion testing and the clinical implications of the results
3. Routine Serologic Testing
Type and Screen
Antibody Identification
Crossmatch
4. Additional Testing
Direct Antiglobulin Test (DAT)
Elution
Adsorption
Phenotyping/Genotyping

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