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Lecture 14: Antiphospholipid Antibody Syndrome

Shruti Chaturvedi, MBBS, MS

Presentation Date: 

January 8, 2026

About This Lecture

  • Antiphospholipid Antibody Syndrome: > A pro-thrombotic syndrome: Clinically syndrome, associated with arterial and/or venous thrombosis, and or pregnancy complications. 

  • Laboratory features: Lupus Anticoagulant, and/or antibodies to beta-2-glycoprotein-1 or cardiolipin. 

  • Despite decades of clinical research and experience, the pathophysiology remains subject to debate.

Speaker Disclosures

Disclosures for Shruti Chaturvedi MBBS
> Consulting – Takeda, Alexion, Sanofi, Novartis, RallyBio, TargED
> Consulting, research support (to institution) – Sanofi, Takeda, Sobi
> Membership on advisory committee / steering committee – Sobi, Alexion, Sanofi, Novartis, Takeda
> Membership on board of directors: Hemostasis and Thrombosis Research Society, USTMA Consortium
> Royalties – UpToDate.com

Learning Objectives

At the end of this presentation, the learner will be able to
Apply updated clinical and laboratory tools for the diagnosis of APS
Identify evidence-based strategies for the treatment of thrombotic APS
Identify pathogenic mechanisms and therapeutic targets for refractory and catastrophic APS

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