Lecture 18: Heparin Induced Thrombocytopenia (HIT)

Gerald A Soff MD

Presentation Date:

February 5, 2026

> Heparin Induced Thrombocytopenia/Thrombosis (HITT) is one of the most dangerous drug reactions.
>HITT is associated with a high risk of morbidity and mortality, if not promptly recognized and managed appropriately.

Gerald A Soff MD
Chief, Classical Hematology Service
Sylvester Comprehensive Cancer Center,
University of Miami Health System
gas199@Miami.edu

Disclosures for Gerald A Soff MD.
Research Support (Past 2 years):
Amgen, Sobi/Dova Pharmaceuticals
Anthos Therapeutics

Data Safety Monitoring Committee
Alpine Immune Sciences

Advisory Boards (Past 2 years)
Sanofi , Novartis

> HITT may lead to severe thrombosis of the aretial, venous, and micro- circulations.

> This case illustrates digital gangere from HITT.

> Images from Cormack GM & Kaufman LJ. Journal of Medical Case Reports 2007, 1:13 doi:10.1186/1752-1947-1-13

Starting in 2025, lectures are eligible for Continuing Education Credit.
Link for CE:

Link For Continuing Education Credit

Access Slide Deck