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Lecture 27: Thrombotic Microangiopathies/TTP

Dr. Mari Thomas
Presentation Date: 
April 18, 2024

> Thrombotic Microangiopathies are a range of disorders, characterized by microvascular thrombosis, non-immune hemolytic anemia, and thrombocytopenia.
> These may be life-threatening, and require prompt diagnosis and appropriate intervention.

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Dr. Mari Thomas
University College London Hospitals, UK
mari.thomas@nhs.net

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Peripheral smear from a patient with sepsis. Note thrombocytopenia, but also schistocytes (Fragmented red cells). This is consistent with Disseminated intravascular coagulation (DIC). (Image from Gerald A Soff MD)

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