This is a classic peripheral smear of a patient with Warm (IgG) Autoimmune Hemolytic Anemia.

Spherocytes are indicative of IgG mediated hemolytic anemia, (or hereditary spherocytosis). 

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The large red cells with a blue color, referred to as polychromatophilia, are young red cells. An increase in young red cells is confirmed with a reticulocyte count and indicates increased red cell production.  

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